The Plague Isn’t a Problem.
For Now.
HELP KEEP IT THAT WAY.
Believe it or not, there is no approved plague vaccine. Research studies are enrolling healthy 18- to 55-year-olds for vaccine testing to keep the plague at bay.
Research studies are enrolling healthy 18-55-year-olds for investigational vaccine testing.
Qualified volunteers may receive:
No-cost study-related care
from local doctors and specialists
Study medication
at no cost
The satisfaction of supporting
the men and women of the
armed services
Research studies are enrolling today!
Protection against the plague and outbreak prevention. There is no FDA-approved plague vaccine, and history has shown that plague can be disfiguring and fatal. This study is designed to test a possible plague vaccine specifically designed to fight the pneumatic form of the disease.
No, absolutely not. The injection we are testing doesn’t contain the plague bacteria and therefore cannot cause plague.
This experimental vaccine starts with an adenovirus (the same virus that causes a cold) that has been weakened so it cannot infect people. Then it is genetically altered so it reacts to plague bacterium to make proteins, which, in turn, teach the immune system to fight off the plague infection should it ever need to. What’s being tested is combining this vaccine with an “adjuvant,” which is an immunological substance that combines with a specific protein (antigen) to supercharge that immune response and provide better protection than with an antigen alone.
Sure, the adjuvant being used is called CpG 1018. In pre-clinical and clinical studies of other vaccine studies (Hepatitis B, COVID-19), it has shown to help increase antibody concentrations and stimulate immune system memory responses.
No, we will never expose you to the plague in any way. We will use clinical methods to measure your body’s immune response.
While rare, the plague poses several threats. While not likely, there is a danger of an outbreak or pandemic that could stress the healthcare system, especially in developing countries. Also, there are some occupations and activities that could put certain populations at greater risk. Veterinarians, military personnel, livestock handlers, hunters, and outdoor enthusiasts in areas where the plague is active all run this risk. We believe in being prepared.
How does study matching work?
Answer some questions
about your health
Tell us a little bit about yourself
Connect to available studies
in your area
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When a flea feeds on an infected host, it becomes a carrier and can interact with people directly or through a pet like a cat or dog.
How Does Study Matching Work?
We’d like to learn more about you in order to find a study that’s a good fit. Studies may have different age or health requirements.
Based on the information you give us, we’ll try to match you to a suitable study in your area. If we can’t find a good match for you, we’ll keep you in mind for future studies and notify you when they become available
The study team will ask questions and check your health to make sure that the study is right for you. This visit can be conducted in person at the study clinic or by an online video call from the comfort of your home
If you join a study, you may be asked to make visits to the study clinic or have online video visits. You may receive an investigational (experimental) vaccine or drug as part of your participation.
Remember,
Telehealth visits are available.
Odds are you’ll never get the plague, but it’s still around in high-risk areas.
That’s why we’re trying to keep the plague at bay.
See if you qualify for this investigational vaccine clinical research study.
Another way to contract plague is by handling the infected skins, flesh or fluids of infected animals.
Obviously, veterinarians and hunters should be especially careful when handling animals.
About Clincal Research
Clinical research studies are research projects done with human volunteers to find out if new vaccines and medications are safe and effective. In clinical research studies, the participants get an investigational vaccine or treatment under the care of a doctor and other medical professionals. The word “investigational” means it isn’t available or approved yet for the regular public.
All clinical research studies are regulated by government agencies. What’s more, they’re reviewed and watched over by panels of qualified doctors, scientists, religious representatives, and other members of the community. These review boards make sure your safety, rights, and welfare are protected, and that the study is being done for ethical and honest reasons. No vaccine or treatment can be completely safe for every person, but research studies help make sure the benefits outweigh the possible risks for most people.
Yes! The study team can’t tell anyone that you’re participating in a research study without your permission. The information collected during research studies is kept confidential, and patient names aren’t listed in any reports based on studies.
Clinical research studies need patients with a healthy mix of racial and ethnic backgrounds because drugs and vaccines can affect different groups differently. It’s very important to understand this before new vaccines and treatments can be approved for everyone to use. Also, some groups may be affected by certain diseases more than others. So it’s important to strive for a diverse group of patients in research studies, as long as they meet the requirements for the studies.
If you get matched to a study and have questions for the study team about safety or other concerns, please ask them! It’s actually very important that all your questions are answered and that you feel comfortable about your participation. Also, keep in mind that you may leave research studies at any time, for any reason. The power is yours!
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